Arrhythmias & electrophysiology

Non-invasive detection of slow conduction with cardiac magnetic resonance imaging for ventricular tachycardia ablation

EuropacePublished Retrospective cohort study

Authors' conclusion

Non-invasive detection of targets for VT ablation is possible with CMR. Deceleration zones found during electroanatomical mapping accurately correlate with CMR channels, especially those with increased length, BZ mass, and protectedness.

Study context

Population
Consecutive patients with structural heart disease and ventricular tachycardia (VT) undergoing ablation after CMR, single centre, October 2018 to July 2021 (mean age 64.8 ± 11.6 years; 95.5% male; 70.5% ischaemic heart disease; mean EF 32.3 ± 7.8%)109 CMR channels analysed
Participants
44 patients
Exposure
CMR channels associated with deceleration zones (DZs) vs channels not associated with DZs
Outcome
Capability of CMR to identify DZs (correlation of CMR channels with DZs on isochronal late activation mapping) and predictors of arrhythmogenicity in CMR channels
Methodological detailssingle-centre, consecutive patients
  • Single-centre
  • Consecutive patients

Main finding

As reported in the abstract

CMR channels associated with a DZ

CMR channels associated with a DZ

76.1%

Observational data: associations, not effects.

Further findings

Channel length (univariate analysis)

OR 1.03 · P = 0.010

Protectedness (univariate analysis)

OR 1.08 · P = 0.021

BZ mass (univariate analysis)

OR 2.46 · P = 0.011

CMR channel characteristics (all channels)

Channels per patient
2.48 ± 1.15
Length
57.91 ± 63.07 mm
Conducting channel mass
2.06 ± 2.67 g
Protectedness
21.44 ± 25.39 mm

Original publication

Non-invasive detection of slow conduction with cardiac magnetic resonance imaging for ventricular tachycardia ablation. Europace. Published 23 January 2024. doi:10.1093/europace/euae025

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