Heart failure & cardiomyopathies

Non-invasive estimation of left ventricular systolic peak pressure: a prerequisite to calculate myocardial work in hypertrophic obstructive cardiomyopathy

Eur Heart J Cardiovasc ImagingPublished Diagnostic accuracy study

Performance · LVSPResult — go to the resultCorrelation r 0.87

Authors' conclusion

Non-invasive estimation of LVSP in HOCM is feasible by combining conventional BP and averaged CWmean and CWmax gradients.

Study context

Population
Patients with hypertrophic obstructive cardiomyopathy (HOCM) with indication for first alcohol septal ablation
Participants
20 consecutive patients
Comparison
Non-invasively derived left ventricular systolic pressure (LVSP) vs invasively measured LVSP
Outcome
Agreement of non-invasively derived LVSP with invasively measured LVSP
Methodological detailsconsecutive patients, simultaneous invasive and non-invasive measurements
  • Consecutive patients
  • Simultaneous invasive and non-invasive measurements

Performance

LVSP

Correlation r

0.87

P < 0.001

By group

As reported in the abstract

Further findings

OutcomeValuesP value
Mean gradient, CathLab vs CW DopplerCathLab mean 34.3 (SD 13.4) mmHg · CW mean 31.0 (SD 13.7) mmHg
Maximal gradient, echocardiography vs CathLabHigher in echocardiographyEchocardiography mean 64.5 (SD 28.8) mmHg · CathLab mean 54.8 (SD 24.0) mmHgP < 0.05

Mean gradient, Catheterization Laboratory (CathLab) vs CW Doppler

Mean gradients of both methods comparable

Original publication

Non-invasive estimation of left ventricular systolic peak pressure: a prerequisite to calculate myocardial work in hypertrophic obstructive cardiomyopathy. Eur Heart J Cardiovasc Imaging. Published 19 September 2023. doi:10.1093/ehjci/jead236

Composed by AI from the published abstract and checked against it. How Briefs are made →

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