Heart failure & cardiomyopathies
Noninvasive assessment of left ventricular performance using pressure–volume loops, blood propulsion and strain tensors: results from the World Alliance of Societies of Echocardiography study
Authors' conclusion
This study analysed a large normal population with physics-based methods that allow a deep mechanical and haemodynamic analysis of 3DE with 70% feasibility and provided reference values for a series of advanced parameters and their dependency on sex, age, and race.
Study context
- Population
- Normal subjects with three-dimensional echocardiography (3DE) data
- Participants
- 1,403 normal subjects
- Comparison
- Differences in noninvasive pressure-volume (PV) loops, intraventricular pressure gradients (IVPG) and left ventricular (LV) strain tensors by sex, age and race
- Outcome
- Sex- and age-related differences in strain and PV loop
Main finding
As reported in the abstract
- Sex- and age-related differences in strain and PV loop are limited to some parameters only
Further findings
Haemodynamic performance in terms of IVPG
- Does not vary with sex and is reduced with aging
Race-related differences
- Asian populations are characterized by smaller hearts, higher EF, strain, and PV loop scores than Whites, which in turn have similar LV size to Blacks and higher EF, strain, and PV loop scores, while IVPG was more similar across the populations
Feasibility
- Feasibility
- 70%
Original publication
Noninvasive assessment of left ventricular performance using pressure–volume loops, blood propulsion and strain tensors: results from the World Alliance of Societies of Echocardiography study. Eur Heart J Cardiovasc Imaging. Published 7 July 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →