Valvular & structural heart disease
Normal reference values for mitral annular plane systolic excursion by motion-mode and speckle tracking echocardiography: a prospective, multicentre, population-based study
Authors' conclusion
Normal MAPSE reference values were established based on age and sex.
Study context
- Population
- Healthy adults aged 18–80 years840 men (43%)
- Participants
- 1,952 adults
- Exposure
- Motion-mode (M-mode) vs 2D-STE
- Outcome
- Normal ranges for MAPSE by M-mode and 2D-STE and its principal determinants
Methodological detailsprospective, multicentre, population-based, 55 centres
- Prospective
- Multicentre
- Population-based
- 55 centres
Main finding
As reported in the abstract
MAPSE reference values
- Women had higher mitral annular plane systolic excursion (MAPSE) than men
- MAPSE decreased with age
- Age- and sex-specific reference values established for both methods
Observational data: associations, not effects.
Further findings
Determinants of MAPSE (multiple linear regression)
- MAPSE on M-mode correlated with age
- MAPSE on 2D-STE correlated with age, blood pressure (BP), heart rate and left ventricular (LV) volume
Correlation with global longitudinal strain
- MAPSE by 2D-STE correlated more strongly with global longitudinal strain than MAPSE by M-mode
Original publication
Normal reference values for mitral annular plane systolic excursion by motion-mode and speckle tracking echocardiography: a prospective, multicentre, population-based study. Eur Heart J Cardiovasc Imaging. Published 2 August 2023. doi:10.
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