Normal values of myocardial blood flow measured with dynamic myocardial computed tomography perfusion
Authors' conclusion
MBF assessed by DM-CTP in healthy individuals with normal coronary arteries displays significant intersegmental heterogeneity which does not seem to be affected by age, sex, or coronary dominance.
Study context
- Population
- Healthy individuals aged 45–78 years with normal coronary arteries by CCTA46 women
- Participants
- 82 individuals
- Exposure
- Rest and stress DM-CTP vs Stress DM-CTP only
- Rest and stress DM-CTPn = 30
- Stress DM-CTP onlyn = 52
- Outcome
- Normal values of MBF measured using DM-CTP
Main finding
As reported in the abstract
Global MBF
Global myocardial blood flow (MBF) at rest (mean ± SD, mL/min/g)
0.93 ± 0.42
Global MBF during stress (mean ± SD, mL/min/g)
3.58 ± 1.14
Observational data: associations, not effects.
Further findings
MBF by sex
- MBF not different between the sexes at rest
- P = 0.88
- MBF not different between the sexes during stress
- P = 0.61
MBF and age
- No correlation between MBF and age at rest
- P = 0.08
- No correlation between MBF and age during stress
- P = 0.82
Regional MBF distribution (16 myocardial segments)
- Significant intersegmental differences, not related to age, sex or coronary dominance
- P < 0.01
Original publication
Normal values of myocardial blood flow measured with dynamic myocardial computed tomography perfusion. Eur Heart J Cardiovasc Imaging. Published 20 February 2024. doi:10.
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