Prevention & lipids

Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis

Circ Cardiovasc ImagingPublished Cross-sectional study

Authors' conclusion

Among a large, diverse group of healthy older adults, we found significant differences in cardiac structure and function by sex and race/ethnicity, which may signal sex-specific cardiac remodeling with advancing age.

Study context

Population
Healthy older adults (≥65 years) without cardiopulmonary or cardiometabolic conditions, MESA exam 6608 healthy aging cohort
Participants
3,032 adults
Outcome
Normative values (mean ± 1.96 SD) of 2D echocardiography chamber size and function

Main finding

As reported in the abstract

Current guidelines identified healthy older adults in MESA as having cardiac abnormalities

81.6%

Observational data: associations, not effects.

Further findings

Functional status (NT-proBNP, 6-minute walk distance, KCCQ)

Normative aging cohort had lower NT-proBNP, higher 6-minute walk distance and higher (better) KCCQ summary values

Original publication

Normative Values of Echocardiographic Chamber Size and Function in Older Healthy Adults: The Multi-Ethnic Study of Atherosclerosis. Circ Cardiovasc Imaging. Published 8 May 2024. doi:10.1161/circimaging.123.016420

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