Arrhythmias & electrophysiology
Omnipolar conduction velocity mapping for ventricular substrate characterization: Impact of conduction velocity (CV) estimation method and electrogram (EGM) type on in vivo conduction velocity measurements
Authors' conclusion
The CV estimation method has an important, statistically significant impact on ventricular CV measurements.
Study context
- Population
- Patients with structurally normal hearts, high-density ventricular contact maps during sinus rhythm (SR) and ventricular ectopy (VE)22 SR and 16 VE maps
- Participants
- 23 patients
- Exposure
- Omnipolar wave speed vs 4 local activation time (LAT)-based CV estimation methods
- Outcome
- Ventricular CV estimates by method
Methodological detailshigh-density contact mapping
- High-density contact mapping
Main finding
As reported in the abstract
CV estimates, WS vs LAT-based methods
| Group | Value | SR maps | VE maps |
|---|---|---|---|
| Wave speed (WS) | mean 1.41 (SD 0.18) m/s | 1.41 ± 0.18 m/s | 1.23 ± 0.18 m/s |
Wave speed (WS)
Valuemean 1.41 (SD 0.18) m/s
SR maps1.41 ± 0.18 m/s
VE maps1.23 ± 0.18 m/s
- WS significantly higher CV than all LAT-based methods in SR and VE; absolute differences
- 0.1 m/s to 0.81 m/s
- Median pointwise differences WS vs LAT-based methods, from WS vs planar wavefront fitting to WS vs radial basis function
- 0.55 ± 0.15 m/s to 0.67 ± 0.16 m/s
Observational data: associations, not effects.
Further findings
CV by EGM type (LAT-based methods, SR)
- Unipolar EGMs gave significantly higher CV than bipolar or omnipolar EGMs
Original publication
Omnipolar conduction velocity mapping for ventricular substrate characterization: Impact of CV estimation method and EGM type on in vivo conduction velocity measurements. Heart Rhythm. Published 6 June 2024. doi:10.
Summarised from the published abstract; every number is checked against it