Arrhythmias & electrophysiology
One-year clinical and safety outcome of obese patients undergoing pulmonary vein isolation for atrial fibrillation with pulsed field ablation or cryoballoon ablation: A propensity-matched analysis
Authors' conclusion
PFA offers an alternative to CBA in obese patients, with superior recurrence outcomes and shorter procedural durations postmatching in this single-center cohort. PFA may be a preferred approach for AF management in this high-risk population. Future randomized trials are warranted to validate these findings and optimize treatment protocols for obese patients with AF.
Study context
- Population
- Symptomatic patients with paroxysmal and persistent atrial fibrillation (AF) and a body mass index (BMI) >30 who underwent pulsed-field ablation (PFA) or cryoballoon ablation (CBA)
- Exposure
- PFA compared with CBA in obese patients with AF
- Outcome
- Recurrence rates
Methodological detailssingle institution
- Single institution
Main finding
As reported in the abstract
P = 0.02
Observational data: associations, not effects.
Further findings
Left atrial (LA) time · significantly shorter with PFA
P < 0.01
Procedural time · significantly shorter with PFA
P < 0.01
Fluoroscopy time
- Fluoroscopy time showed no significant difference
Safety outcomes
- Safety outcomes were similar across both groups
Original publication
One-year clinical and safety outcome of obese patients undergoing pulmonary vein isolation for atrial fibrillation with pulsed field ablation or cryoballoon ablation: A propensity-matched analysis. Heart Rhythm. Published 4 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →