Acute cardiac care & resuscitation
Outcomes after extracorporeal cardiopulmonary resuscitation in pediatric in-hospital cardiac arrest: does quality of CPR matter?
Authors' conclusion
While adherence to AHA guideline-complaint CPR was not significantly associated with SHD, patient age and CPR duration were significant predictors. These findings emphasize the need to better understand factors associated with survival after pediatric ECPR while also helping to drive improvements in ECPR care models.
Study context
- Population
- Children (<18 years) with IHCA requiring ECMO to achieve ROSC (ECPR)index ECPR events (> 5 epochs) with CPR quality metric data from 20 sites · infants (<1 year) 62 · children (1-<8 years) 52 · adolescents (8-≤18 years) 43
- Participants
- 157 index ECPR events
- Exposure
- Guideline-compliant CPR vs not guideline-compliant CPR, and survival to hospital discharge (SHD)
- Outcome
- SHD by guideline compliance
Methodological detailsfrom PediRES-Q, 20 sites
- From PediRES-Q
- 20 sites
Main finding
As reported in the abstract
- Guideline compliance was not significantly associated with SHD after adjusted logistic regression
- Controlling for age, arterial line, duration of CPR, and clustering by site
Observational data: associations, not effects.
Further findings
Overall guideline compliance by age group
| Outcome | aOR (CI) | P value | |
|---|---|---|---|
| SHD by age8-<18 yearsvs < 8 year64% lower odds of SHD | 0.36 (0.17–0.76) | P = 0.007 | |
| 0.10.31310Adjusted odds ratio (log scale) |
Cohort characteristics
- With a cardiac diagnosis
- 74/157 (47%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes after extracorporeal cardiopulmonary resuscitation in pediatric in-hospital cardiac arrest: does quality of CPR matter? Resuscitation. Published 7 April 2025. doi:10.
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