Acute cardiac care & resuscitation
Long-term health-related quality of life in survivors of extracorporeal cardiopulmonary resuscitation compared to conventional cardiopulmonary resuscitation- A cohort study using Australian and New Zealand extracorporeal membrane oxygenation registry and the Victorian Ambulance Cardiac Arrest Registry
Authors' conclusion
Despite significant baseline differences between ECPR and CCPR, there were no differences in HRQoL at 12 months.
Study context
- Population
- Adult patients with out-of-hospital cardiac arrest (OHCA) with cardiac arrest and 12-month health-related quality of life (HRQoL) data recorded between July 2019 and July 2023 (EXCEL registry for extracorporeal cardiopulmonary resuscitation (ECPR), Victorian Ambulance Cardiac Arrest Registry (VACAR) for conventional cardiopulmonary resuscitation (CCPR))24 ECPR and 754 CCPR survivors had HRQoL data · ECPR survivors at 12 months 33/122(28%) · CCPR survivors at 12 months 1,074/8,990(12%) · ECPR survivors with HRQoL data 24 (73%) · CCPR survivors with HRQoL data 754 (70%)
- Participants
- 24 vs 754
- Exposure
- ECPR vs CCPR for OHCA
- ECPRn = 24
- CCPRn = 754
- Outcome
- EQ-5D-5L utility score and EQ-VAS
- Follow-up
- 12 months
Main finding
As reported in the abstract
| Group | EQ-5D-5L utility score | EuroQol visual analogue score (EQ-VAS) |
|---|---|---|
| ECPR | 0.95 (0.72-1) | 80 (64.5-90) |
| CCPR | 0.96 (0.86-1) | 75 (60-85) |
EQ-5D-5L utility score
ECPR0.95 (0.72-1)
CCPR0.96 (0.86-1)
EuroQol visual analogue score (EQ-VAS)
ECPR80 (64.5-90)
CCPR75 (60-85)
- ECPR vs CCPR: P = 0.64 — EQ-5D-5L utility score
- ECPR vs CCPR: P = 0.39 — EQ-VAS
Observational data: associations, not effects.
Further findings
| Outcome | ECPR | CCPR | P value |
|---|---|---|---|
| Baseline characteristics | |||
| Age, mean(SD) | 50.4(13.46) yrs | 60.5(14.01) yrs | P < 0.01 |
| Bystander CPR | 19(79%) | 397(52%) | P < 0.001 |
| Arrest to ROSC/ECMO time, median (IQR) | 61(41.5-97) minutes | 6(2-14) minutes | P < 0.001 |
Baseline characteristics
- Similar proportions of males, witnessed arrests and initial shockable rhythms
Original publication
Long-term health-related quality of life in survivors of extracorporeal cardiopulmonary resuscitation compared to conventional cardiopulmonary resuscitation- A cohort study using Australian and New Zealand extracorporeal membrane oxygenation registry and the Victorian Ambulance Cardiac Arrest Registry. Resuscitation. Published 3 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →