Acute cardiac care & resuscitation
Outcomes with intracoronary vs. intravenous epinephrine in cardiac arrest
Authors' conclusion
In this observational study, IC epinephrine during cardiac arrest in the cath lab appeared to be safe and may be associated with improved outcomes compared with the IV route.
Study context
- Population
- Patients with cardiac arrest in the cath lab at two tertiary centres in Egypt, January 2015 to July 2022
- Participants
- 162 patients
- Exposure
- Intracoronary (IC) vs intravenous (IV) epinephrine
- ICn = 52
- IVn = 110reference
- Outcome
- Survival to hospital discharge
Methodological detailstwo tertiary centres
- Two tertiary centres
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
ROSC
P < 0.001
Favourable neurological outcome at discharge (MRS <3)
P < 0.001
Time-to-ROSC
P < 0.0001
Original publication
Outcomes with intracoronary vs. intravenous epinephrine in cardiac arrest. Eur Heart J Qual Care Clin Outcomes. Published 15 February 2023. doi:10.
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