Heart failure & cardiomyopathies

Outpatient Treatment of Worsening Heart Failure with Intravenous Diuretics: First Results from a Multicentre 2-Year Experience

ESC Heart FailPublished Retrospective observational study

Authors' conclusion

Outpatient treatment with intravenous diuretics of patients with WHF is a safe alternative strategy compared with the same treatment in hospitalized patients.

Study context

Population
Adults with worsening heart failure (HF) (all types: Heart failure with reduced ejection fraction (HFrEF), heart failure with mildly reduced ejection fraction (HFmrEF), heart failure with preserved ejection fraction (HFpEF)), weight gain >2 kg, not responding to uptitrated oral diuretics, treated with IV loop diuretics at the outpatient department322 outpatient treatments
Participants
259 adults
Outcome
HF rehospitalisation and all-cause mortality after outpatient IV diuretic treatment of worsening heart failure (WHF)
Follow-up
30 days and 1 year
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

30 days and 1 year

HF rehospitalisation at 30 days

30.5%

HF rehospitalisation at 1 year

53.3%

All-cause mortality at 30 days

5.8%

All-cause mortality at 1 year

26.3%

Observational data: associations, not effects.

Safety

Adverse events in 322 individual outpatient treatments
1

Original publication

Outpatient Treatment of Worsening Heart Failure with Intravenous Diuretics: First Results from a Multicentre 2-Year Experience. ESC Heart Fail. Published 14 November 2022. doi:10.1002/ehf2.14168

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