Arrhythmias & electrophysiology
P-Wave Durations from Automated Electrocardiogram Analysis to Predict Atrial Fibrillation and Mortality in Heart Failure
Authors' conclusion
Extreme values of maximum P-wave durations (≤90 ms and ≥141 ms) were significant predictors of new-onset AF, cardiovascular mortality, and all-cause mortality.
Study context
- Population
- Consecutive Chinese patients admitted with heart failure (HF) without prior atrial fibrillation (AF), with ≥1 baseline ECG, single tertiary centre, 2010–2016
- Participants
- 2,718 patients
- Exposure
- Maximum P-wave duration categories vs 101-120 ms
- Outcome
- New-onset AF, CV mortality, all-cause mortality by maximum P-wave duration
- Follow-up
- Median 4.8 years
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
Each group vs 101-120 msHazard ratio (CI)P value
≤90 msnew-onset AF
1.17(1.11–1.50)
P < 0.01131-140 msnew-onset AF
1.29(1.09–1.54)
P < 0.001≥141 msnew-onset AF
1.52(1.32–1.75)
P < 0.001≤90 msCV mortality
1.50(1.08–2.06)
P < 0.001≥141 msCV mortality
1.18(1.15–1.45)
P < 0.001≤90 msall-cause mortality
1.26(1.04–1.51)
P < 0.001131-140 msall-cause mortality
1.15(1.01–1.32)
P < 0.01≥141 msall-cause mortality
1.31(1.18–1.46)
P < 0.001Patients
- New-onset AF
- 1150 (8.8/year)
- Stroke
- 339 (2.6/year)
- CV mortality
- 563 (4.3/year)
- All-cause mortality
- 1972 (15.1/year)
Observational data: associations, not effects.
Original publication
P-Wave Durations from Automated Electrocardiogram Analysis to Predict Atrial Fibrillation and Mortality in Heart Failure. ESC Heart Fail. Published 2 December 2022. doi:10.
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