Arrhythmias & electrophysiology

Automated interpretations of single-lead electrocardiograms predict incident atrial fibrillation: The VITAL-AF trial

Heart RhythmPublished Secondary analysis of the VITAL-AF randomised trial

Authors' conclusion

In patients undergoing AF screening with 1L ECGs without prevalent AF or AF within 60 days of screening, presumptive positive and indeterminate 1L ECG interpretations were associated with future AF.

Study context

Population
Participants in the VITAL-AF atrial fibrillation (AF) screening trial without prevalent AF
Participants
16,306 / 10,914 / 2,675 / 561
Comparison
Automated 1L ECG interpretation categories
  • Never screenedn = 16,306
  • Normaln = 10,914reference
  • Othern = 2,675
  • Possible AFn = 561
Primary endpoint
Incident AF (follow-up starting 60 days after the latest 1L ECG)

Primary result

As reported in the abstract

Incident AF

Possible AF

5.91

incidence · 95% CI 4.24–8.23 · per 100 person-years

Each group vs normalAdjusted hazard ratio (95% CI)
Possible AF
2.48(1.66–3.71)
Other
1.41(1.04–1.90)

Original publication

Automated interpretations of single-lead electrocardiograms predict incident atrial fibrillation: The VITAL-AF trial. Heart Rhythm. Published 29 April 2024. doi:10.1016/j.hrthm.2024.04.085

Composed by AI from the published abstract and checked against it. How Briefs are made →

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