Congenital heart disease

Pacemaker Management and In-Hospital Outcomes in Neonatal Congenital Atrioventricular Block

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

Over 18.5 years, in-hospital mortality occurred in 36.2% of nCAVB patients with CHD and 8.4% with non-CHD. Associations with increased in-hospital mortality included CHD and prematurity and decreased with pacemaker placement.

Study context

Population
Patients <31 days of age with neonatal congenital atrioventricular block (nCAVB) and no cardiac surgeries except pacemaker, 2004–2022
Participants
1,146 patients
Exposure
nCAVB with congenital heart disease (CHD) vs without CHD; pacing strategies
  • CHDn = 326
  • Non-CHDn = 820reference
Outcome
In-hospital mortality
Methodological detailsmulticenter database, Pediatric Health Information System, 659 (57.5%) girls; 506 (44.2%) premature
  • Multicenter database
  • Pediatric Health Information System
  • 659 (57.5%) girls; 506 (44.2%) premature

Main finding

As reported in the abstract

Over 18.5 years

Observational data: associations, not effects.

Further findings

OutcomeCHDNon-CHD
Initial intervention and temporary pacing
Pacemaker as initial intervention134 (41.1%)334 (40.7%)
Temporary pacing wires56 (17.2%)81 (9.9%)

Original publication

Pacemaker Management and In-Hospital Outcomes in Neonatal Congenital Atrioventricular Block. JACC Clin Electrophysiol. Published 21 June 2023. doi:10.1016/j.jacep.2023.05.003

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