Heart failure & cardiomyopathies
Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management
Authors' conclusion
Definition of PiCM varied significantly between studies. More than 1 in 10 patients with chronic right ventricular pacing developed PiCM. Key risk factors included baseline left ventricular ejection fraction, native QRS duration, RV pacing percentage, and paced QRS duration.
Study context
- Population
- Patients with RV pacing after pacemaker implantation
- Participants
- 57,993 patients26 studies
- Outcome
- Pooled prevalence of pacing-induced cardiomyopathy (PiCM)
Methodological detailsrandom-effects
- Random-effects
Pooled result
As reported in the abstract
Pooled prevalence of PiCM
Pooled prevalence of pacing-induced cardiomyopathy (PiCM)
12%
95% CI 11%–14%
Further pooled results
Definitions of PiCM
- Unique definitions of PiCM reported
- 15
Risk factors for PiCM
- Risk factors: male sex, history of MI, CKD, AF, baseline LVEF, native QRS duration, RV pacing percentage, paced QRS duration
Treatment strategies
- Biventricular CRT (studies)
- 6
- His-bundle pacing (studies)
- 3
Original publication
Pacing-induced cardiomyopathy: A systematic review and meta-analysis of definition, prevalence, risk factors, and management. Heart Rhythm. Published 7 November 2022. doi:10.
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