Heart failure & cardiomyopathies

Paediatric Heart Transplantation During the COVID-19 Pandemic in Iran: Single-Centre Experience

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

Throughout the pandemic, although we experienced a reduction in the transplant rate in the first year, with the increasing vaccination rate in health care and later in the general population, we continued to maintain our transplant rate by incorporating safety protocols and more resources.

Study context

Population
Paediatric heart transplant recipients, single centre in Iran
Participants
59 vs 62
Exposure
Paediatric heart transplantation during the COVID-19 pandemic vs before the pandemic
  • February 2020 to February 2022n = 59
  • February 2018 to 2020n = 62reference
Outcome
Transplant rate and early outcomes during the pandemic
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Heart transplant rate in first pandemic year vs year before the pandemic: reduced
34%
Heart transplant rate in second pandemic year: increase
19%
In-hospital mortality rate during the 2-year pandemic
11.8%
In-hospital COVID-19 infection rate
11 patients (18%)
Overall 30-day survival rate
88%
30-day rejection rate
10%

Observational data: associations, not effects.

Further findings

Echocardiographic function during first month of follow-up

Mean LVEF
53.6 ± 4.9
Mean LV global longitudinal strain
−16.9 ± 3.3
Mean RV global longitudinal strain
−17.0 ± 3.8
No significant difference between patients with in-hospital COVID and other recipients
P = 0.1, P = 0.2 and P = 0.2

Death related to COVID-19 acute respiratory distress syndrome

Deaths related to COVID-19 ARDS
1

Original publication

Paediatric Heart Transplantation During the COVID-19 Pandemic in Iran: Single-Centre Experience. ESC Heart Fail. Published 21 June 2023. doi:10.1002/ehf2.14443

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