Arrhythmias & electrophysiology

Paradigm Shift for Catheter Ablation of Atypical Atrioventricular Nodal Re-Entrant Tachycardia: 3-Dimensional Mapping-Based Ablation

JACC Clin ElectrophysiolPublished Mechanistic study

Authors' conclusion

Catheter ablation targeting the exit sites of LIE or RIE mapped at the CS or TA holds promise as an effective and safe alternative approach to the current targets of ablation for atypical AVNRT cases.

Study context

Population
Patients with atypical AVNRT (fast/slow or slow/slow) undergoing electrophysiological study and ablation14 with atypical AVNRT
Participants
42 patients
Outcome
Exit site of earliest retrograde atrial activation during atypical AVNRT

Main finding

As reported in the abstract

Exit sites solely inside the coronary sinus (CS) (left inferior extension, LIE)
7 patients
Exit sites solely in right postero-septal tricuspid annulus (right inferior extension, RIE)
3
Both LIE and RIE exits
4
Distance from CS ostium to LIE exits (mm)
14 ± 6
RIE exits on tricuspid annulus (TA) posterior to CS ostium (LAO projection)
between 5 and 6 o'clock

Further findings

Long-term elimination of AVNRT with ablation targeting exits or conventional slow pathway

Success
13 of the 14 patients (93%)

Safety

Complications
0

Original publication

Paradigm Shift for Catheter Ablation of Atypical Atrioventricular Nodal Re-Entrant Tachycardia: 3-Dimensional Mapping-Based Ablation. JACC Clin Electrophysiol. Published 21 June 2023. doi:10.1016/j.jacep.2023.04.028

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