Arrhythmias & electrophysiology
Substrate Imaging Before Catheter Ablation of Ventricular Tachycardia: Risk Prediction for Acute Hemodynamic Decompensation
Authors' conclusion
Addition of TSV to a modified PAINESD score, PAINES2D, enhances risk prediction of AHD.
Study context
- Population
- Patients with structural heart disease undergoing index ventricular tachycardia (VT) ablation, 2017–2022with total scar volume (TSV) data
- Participants
- 61 patients
- Exposure
- PAINES2D vs PAINESD for prediction of acute hemodynamic decompensation (AHD)
- Outcome
- Periprocedural acute hemodynamic decompensation (AHD)
- Follow-up
- Periprocedural
Methodological detailssingle-centre, quaternary care center
- Single-centre
- Quaternary care center
Main finding
As reported in the abstract
Prediction of AHD
| Group | AUC | Association with AHD |
|---|---|---|
| PAINES2D | 0.73 (95% CI: 0.56-0.91; P = 0.011) | P = 0.010 |
| PAINESD | 0.67 (95% CI: 0.49-0.85; P = 0.058) | P = 0.046 |
AUC
PAINES2D0.73 (95% CI: 0.56-0.91; P = 0.011)
PAINESD0.67 (95% CI: 0.49-0.85; P = 0.058)
Association with AHD
PAINES2DP = 0.010
PAINESDP = 0.046
- Periprocedural AHD
- 13 (21%)
Observational data: associations, not effects.
Further findings
| Outcome | OR | P value |
|---|---|---|
| TSV and AHDHighest TSV tertile (≥37.30 mL) vs Other tertiles | 4.80 | P = 0.018 |
- TSV and AHD — TSV associated with AHD
- P = 0.016
- TSV and AHD — PAINESD associated with AHD
- P = 0.053
TSV and AHD
- TSV and PAINESD independently associated with AHD risk
Original publication
Substrate Imaging Before Catheter Ablation of Ventricular Tachycardia: Risk Prediction for Acute Hemodynamic Decompensation. JACC Clin Electrophysiol. Published 21 June 2023. doi:10.
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