Heart failure & cardiomyopathies

Pathophysiology and Clinical Use of Agents with Vasodilator Properties in Acute Heart Failure. A Scientific Statement of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)

Eur J Heart FailPublished Scientific statement

Recommendations

As issued by the authors

  1. No firm recommendation suggesting vasodilator treatment over usual care

  2. Acute heart failure (AHF) trial design should consider phenotype diversity of AHF patients

  3. New RCTs should focus on subgroups that may mechanistically benefit from vasodilators, possibly enrolling close to decompensation, e.g. in the ED

Original publication

Pathophysiology and Clinical Use of Agents with Vasodilator Properties in Acute Heart Failure. A Scientific Statement of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur J Heart Fail. Published 4 May 2025. doi:10.1002/ejhf.3673

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