Prevention & lipids

Patterns in Cardiovascular Risk Factors Stratified by Age and Sex in a Large German Population

JACC AdvPublished cross-sectional analysis of medical checkup data

Authors' conclusion

The study underscores the need for sex- and age-specific CV prevention in the working environment. Participants demonstrated escalating CV risk, particularly with increasing age (45-55 years). This highlights the need for targeted measures for this age group, including the menopausal phase in women.

Study context

Population
German working population; employees of German companies attending medical checkups with ias PREVENTcheckups evaluated
Participants
40,704 participants
Exposure
Distribution of cardiovascular (CV) risk factors with a focus on sex-specific differences
Outcome
Cohort characteristics
Methodological detailsstratified by sex and age into 6 groups
  • Stratified by sex and age into 6 groups

Main finding

As reported in the abstract

Average age

49 years

Women

25%

Observational data: associations, not effects.

Further findings

Prevalence of hypertension, elevated low-density lipoprotein, and diabetes

Hypertension

Elevated low-density lipoprotein

Diabetes

Smoking, ages 45 to 55 years

A higher proportion of women than men smoked

Obesity prevalence

Higher in women than in men starting at the age of 50

Diabetes prevalence by age

Higher in women than men under 45 but reversed in men above 55 years

Original publication

Patterns in Cardiovascular Risk Factors Stratified by Age and Sex in a Large German Population. JACC Adv. Published 19 August 2026. doi:10.1016/j.jacadv.2026.103159

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