Congenital heart disease

Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries

HeartPublished international cross-sectional investigation

Authors' conclusion

Large intercountry disparities in PROs were observed. APPROACH-IS II is a pioneering international endeavour that comprehensively evaluated PROs among adults with CHD, drawing participants from nations with different income levels.

Study context

Population
Adults with congenital heart disease (CHD) from 53 centres across 32 countriespatients from 53 centres across 32 countries
Participants
8,415 adults
Exposure
Patient-reported outcomes (PROs) across countries and by country income level
Outcome
Intercountry disparities in PROs

Main finding

As reported in the abstract

  • Large intercountry disparities in PROs were observed

Observational data: associations, not effects.

Further findings

Physical functioning, self-rated health and quality of life (QoL)

Switzerland demonstrated the highest mean scores; Senegal had the lowest scores

Mental health

Malta demonstrated the highest mean scores; Senegal had the lowest scores

Depressive symptoms and anxiety

Pakistan had the lowest mean scores; Turkey had the highest scores

Physical functioning, mental functioning and QoL by country income level

Patients from high-income nations reported significantly better physical functioning, mental functioning and QoL

Original publication

Perceived health, psychological distress and quality of life in 8415 adults with congenital heart disease from 32 countries. Heart. Published 27 June 2025. doi:10.1136/heartjnl-2024-325296

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.