Percutaneous Pulmonary Flow Restriction in Infants With Congenital Heart Disease
Authors' conclusion
Percutaneous PBF restriction appears to be safe and a less invasive option to delay surgical intervention in a select population to allow for somatic growth and gestational maturation.
Study context
- Population
- Neonates with congenital heart disease (CHD) resulting in left-sided obstruction, selected for low birth weight or prematurity
- Participants
- 7 neonates
- Outcome
- Restriction of PBF
Main finding
As reported in the abstract
- All patients had restricted pulmonary blood flow (PBF); mean oxygen saturation decreased from 95% to 84%
- All patients proceeded to full surgical intervention
Observational data: associations, not effects.
Further findings
Presurgical catheterization hemodynamics (5 patients)
- Mean pulmonary vascular resistance
- 1.52 WU × m²
- Mean transpulmonary gradient
- 5.9 mm Hg
- Adequate limitation of PBF
- 5 patients
Safety
Pulmonary artery band placement due to over-circulation · 5 days after the procedure
- Patients requiring PA band
- One patient
Device embolization or need for pulmonary arterioplasty
- All patients proceeded to full surgical intervention without device embolization or need for pulmonary arterioplasty
Original publication
Percutaneous Pulmonary Flow Restriction in Infants With Congenital Heart Disease. JACC Adv. Published 7 June 2024. doi:10.
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