Pulmonary vascular disease & thromboembolism
Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies
Authors' conclusion
Procedure-related complications with BPA, including hemoptysis/vascular injury, lung injury/reperfusion edema, mechanical ventilation, and death, were less common in the second period (2018-2022), compared with first period (2013-2017), likely from refinement in patient and lesion selection and procedural technique over time.
Study context
- Population
- Patients with inoperable, medically refractory chronic thromboembolic pulmonary hypertension undergoing balloon pulmonary angioplasty (BPA)26 articles
- Participants
- 1,714 patients
- Comparison
- BPA complications, 2018-2022 vs 2013-2017
- Outcome
- Procedure-related complications
- Follow-up
- Average 7.3 months
Pooled result
As reported in the abstract
| Group | Hemoptysis/vascular injury | Lung injury/reperfusion edema | Invasive mechanical ventilation | Mortality |
|---|---|---|---|---|
| 2013-2017 | 14.1% (474/3,351) | 11.3% (377/3,351) | 0.7% (23/3,195) | 2.0% (13/636) |
| 2018-2022 | 7.7% (233/3,029) | 1.4% (57/3,943) | 0.1% (4/3,062) | 0.8% (8/1,071) |
Hemoptysis/vascular injury
2013-201714.1% (474/3,351)
2018-20227.7% (233/3,029)
Lung injury/reperfusion edema
2013-201711.3% (377/3,351)
2018-20221.4% (57/3,943)
Invasive mechanical ventilation
2013-20170.7% (23/3,195)
2018-20220.1% (4/3,062)
Mortality
2013-20172.0% (13/636)
2018-20220.8% (8/1,071)
- 2018-2022 vs 2013-2017: P < 0.01 — hemoptysis/vascular injury
- 2018-2022 vs 2013-2017: P < 0.01 — lung injury/reperfusion edema
- 2018-2022 vs 2013-2017: P < 0.01 — invasive mechanical ventilation
- 2018-2022 vs 2013-2017: P < 0.01 — mortality
Original publication
Periprocedural Complications With Balloon Pulmonary Angioplasty: Analysis of Global Studies. JACC Cardiovasc Interv. Published 22 March 2023. doi:10.
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