Valvular & structural heart disease
Persistence of residual shunt at 6 and 12 months after transoesophageal echocardiography-guided percutaneous closure of a patent foramen ovale for cryptogenic stroke
Authors' conclusion
Residual right-to-left shunts are common at 6 months after percutaneous closure of PFO. However, the majority are small and two-thirds of residual right-to-left shunts achieve complete closure between 6 and 12 months.
Study context
- Population
- Consecutive patients undergoing transoesophageal echocardiography-guided patent foramen ovale (PFO) closure for cryptogenic stroke, 2006–2021, with echocardiographic follow-up including contrast bubble study and Valsalva manoeuvremean age 43±11 years
- Participants
- 227 patients
- Outcome
- Prevalence and grade of residual right-to-left shunt after percutaneous PFO closure (transthoracic echocardiography)
- Follow-up
- 6 and 12 months
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Residual right-to-left shunt
- 6 months: no residual shunt
- 72.7%
- 6 months: small residual shunt
- 12.3%
- 6 months: moderate residual shunt
- 6.6%
- 6 months: large residual shunt
- 8.4%
- 12 months: any residual shunt (all patients)
- 12.3%
- 12 months: small residual shunt
- 6.6%
- 12 months: moderate residual shunt
- 2.6%
- 12 months: large residual shunt
- 3.1%
Observational data: associations, not effects.
Original publication
Persistence of residual shunt at 6 and 12 months after transoesophageal echocardiography-guided percutaneous closure of a patent foramen ovale for cryptogenic stroke. Heart. Published 9 August 2024. doi:10.
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