Arrhythmias & electrophysiology
Personalized voltage maps guided by cardiac magnetic resonance in the era of high-density mapping
Authors' conclusion
Personalized voltage CMR-guided personalized voltage maps enable a better identification of the substrate with a higher correlation with both DZs and VT isthmuses than do conventional voltage maps using fixed thresholds.
Study context
- Population
- Patients with scar-related ventricular tachycardia (VT) undergoing ablation after cardiac magnetic resonance (CMR) (October 2018 to December 2020)25 (78.1%) ischemic cardiomyopathy
- Participants
- 32 patients
- Comparison
- Personalized CMR-guided voltage thresholds vs standard thresholds
- Outcome
- Diagnostic yield: DZs identified as border zone tissue and VT isthmuses correlated with a voltage channel
Methodological detailsconsecutive patients
- Consecutive patients
Performance
As reported in the abstract
DZs identified as border zone tissue (of 52)
VT isthmuses correlated with a voltage channel (of 31)
- Personalized thresholds vs Standard thresholds: P = 0.003 — deceleration zones (DZs) as border zone tissue
- Personalized thresholds vs Standard thresholds: P = 0.005 — VT isthmuses correlated with voltage channel
Further findings
Adjusted cutoff bipolar voltages best matching CMR images
- Adjusted lower cutoff
- 0.51 ± 0.32 mV
- Adjusted upper cutoff
- 1.79 ± 0.71 mV
- High interindividual variability
- from 0.14-1.68 to 0.7-3.21 mV
Original publication
Personalized voltage maps guided by cardiac magnetic resonance in the era of high-density mapping. Heart Rhythm. Published 25 April 2024. doi:10.
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