Heart failure & cardiomyopathies
Physician-Directed Patient Self-Management in Heart Failure Using Left Atrial Pressure: Interim Insights from the VECTOR-HF I and IIa Studies
Authors' conclusion
Interim findings suggest that PSM using a LAP monitoring system is feasible and safe.
Study context
- Population
- NYHA class II and III heart failure (HF) patients with an implanted left atrial pressure (LAP) sensorinterim analysis
- Participants
- 13 participants
- Exposure
- LAP-guided patient self-management vs period prior to patient self-management (PSM)
- PSMn = 13
- Outcome
- Ability to perform LAP measurements and transmit data to the HCP interface and patient guidance application; safety outcomes
- Follow-up
- 12 months
Methodological detailsVECTOR-HF I and IIa, open-label
- VECTOR-HF I and IIa
- Open-label
Main finding
As reported in the abstract
- Failures to obtain sensor measurements and transmit data to healthcare provider (HCP) interface and patient guidance application
- 0
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Annualized HF hospitalization rate, PSM vs similar period before PSM · 11.84 months0 admissions vs. 0.69 admissions over 11.84 months · interim analysis | P = 0.004 |
Patient adherence
- Patient adherence
- 91.4%
- Interim analysis
6-min walk test distance and KCCQ overall summary score · 6 months
- Significant improvement in 6-min walk test distance and KCCQ overall summary score
Safety
| Outcome | Values |
|---|---|
| Procedure- or device-related major adverse CV or neurological events · 12 monthsInterim analysis | PSM 0 events |
Original publication
Physician-Directed Patient Self-Management in Heart Failure Using Left Atrial Pressure: Interim Insights from the VECTOR-HF I and IIa Studies. Eur J Heart Fail. Published 20 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →