Arrhythmias & electrophysiology

Implications of the anatomy of papillary muscle connections for mapping and ablation of focal ventricular arrhythmias

Heart RhythmPublished Case series

Authors' conclusion

In more than a third of patients with PAP VAs, VAs originate from connections between PAPs and the surrounding myocardium or between other PAPs. VA electrocardiographic morphologies are different when VAs originate from PAP-connection sites as compared with VAs originating from the PAP body.

Study context

Population
Patients with frequent papillary muscle arrhythmias referred for ablation43 consecutive patients
Participants
17 vs 41
Exposure
Ventricular arrhythmias (VAs) from PAP-myocardial connections vs PAP body
  • PAP-MYCn = 17
  • PAP bodyn = 41reference
Outcome
VA origin from PAP-MYC
Methodological detailsconsecutive patients, multimodality imaging
  • Consecutive patients
  • Multimodality imaging

Main finding

As reported in the abstract

PAP-MYC

40%

17

PAP inserted into mitral valve anulus (of 17 PAP-MYC patients)
5

Observational data: associations, not effects.

Further findings

Delayed R-wave transition

P < 0.001

OutcomeP value
Number of PAP-MYCs per patient, failed vs other proceduresP < 0.001
  • Number of PAP-MYCs per patient, failed vs other procedures: Failed procedures 24.8 ± 8 PAP-MYCs per patient
  • Number of PAP-MYCs per patient, failed vs other procedures: Other procedures 16 ± 7 PAP-MYCs per patient

Original publication

Implications of the anatomy of papillary muscle connections for mapping and ablation of focal ventricular arrhythmias. Heart Rhythm. Published 16 June 2023. doi:10.1016/j.hrthm.2023.06.009

Composed by AI from the published abstract and checked against it. How Briefs are made →

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