Arrhythmias & electrophysiology
Implications of the anatomy of papillary muscle connections for mapping and ablation of focal ventricular arrhythmias
Authors' conclusion
In more than a third of patients with PAP VAs, VAs originate from connections between PAPs and the surrounding myocardium or between other PAPs. VA electrocardiographic morphologies are different when VAs originate from PAP-connection sites as compared with VAs originating from the PAP body.
Study context
- Population
- Patients with frequent papillary muscle arrhythmias referred for ablation43 consecutive patients
- Participants
- 17 vs 41
- Exposure
- Ventricular arrhythmias (VAs) from PAP-myocardial connections vs PAP body
- PAP-MYCn = 17
- PAP bodyn = 41reference
- Outcome
- VA origin from PAP-MYC
Methodological detailsconsecutive patients, multimodality imaging
- Consecutive patients
- Multimodality imaging
Main finding
As reported in the abstract
PAP-MYC
40%
17
- PAP inserted into mitral valve anulus (of 17 PAP-MYC patients)
- 5
Observational data: associations, not effects.
Further findings
Delayed R-wave transition
P < 0.001
| Outcome | P value |
|---|---|
| Number of PAP-MYCs per patient, failed vs other procedures | P < 0.001 |
- Number of PAP-MYCs per patient, failed vs other procedures: Failed procedures 24.8 ± 8 PAP-MYCs per patient
- Number of PAP-MYCs per patient, failed vs other procedures: Other procedures 16 ± 7 PAP-MYCs per patient
Original publication
Implications of the anatomy of papillary muscle connections for mapping and ablation of focal ventricular arrhythmias. Heart Rhythm. Published 16 June 2023. doi:10. 1016/ j. hrthm. 2023. 06. 009
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