Arrhythmias & electrophysiology
PPG-based smartphone application vs usual care for atrial fibrillation screening: A European multicenter randomized trial
Authors' conclusion
In this multicenter trial, application usage in combination with early intervention did not significantly increase overall AF detection rates.
Study context
- Population
- Patients with no prior atrial fibrillation (AF)
- Participants
- 1,021 patients8 centres
- Comparison
- PPG-based smartphone application with early intervention vs sham
- Primary endpoint
- AF detection rate
Methodological detailsinternational, multicentre, prospective, sham-controlled, double-blind, Conducted October 2019 to May 2024, Randomised 1:1
- International
- Multicentre
- Prospective
- Sham-controlled
- Double-blind
- Conducted October 2019 to May 2024
- Randomised 1:1
Primary result
As reported in the abstract
AF detection
P = 0.094
Further findings
Asymptomatic AF detection
P = 0.13
Arrhythmia detected
Mean
| Outcome | Intervention | Sham |
|---|---|---|
| CHA2DS2-VASc score | 3.4 (SD 0.92) | 3.5 (SD 1.02) |
- Arrhythmia detected — Arrhythmia detected overall
- 32 (3.1%)
- Arrhythmia detected — AF diagnosed overall
- 13 (1.3%)
Stroke, TIA or systemic embolism · 6 months
- No difference between groups
Original publication
PPG-based smartphone application vs usual care for atrial fibrillation screening: A European multicenter randomized trial. Heart Rhythm. Published 16 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →