Arrhythmias & electrophysiology
Total Atrial Conduction Time as a Predictor of Left Atrial Functional Recovery in Atrial Fibrillation
Main finding · Association of preprocedural PA-TDI duration with LARS at 6 monthsResult — go to the resultStandardized beta −0.20 95% CI −0.10 to −0.01Authors' conclusion
The measurement of PA-TDI duration provided valuable information for LA functional recovery in AF patients who underwent CA.
Study context
- Population
- Atrial fibrillation (AF) patients in sinus rhythm at preprocedural echocardiography undergoing first catheter ablation
- Participants
- 109 patients
- Exposure
- Longer vs shorter preprocedural PA-TDI duration
- Outcome
- LA reservoir strain (LARS) after catheter ablation, predicted by preprocedural PA-TDI duration
- Follow-up
- 6 months after CA
Methodological detailsMedian follow-up 465 (273-746) days
- Median follow-up 465 (273-746) days
Main finding
As reported in the abstract
Association of preprocedural PA-TDI duration with LARS at 6 months
Standardized beta
−0.20
95% CI −0.10 to −0.01
P = 0.013
- Median PA-TDI duration
- 144 (128-162) ms
Observational data: associations, not effects.
Further findings
LA reservoir strain (LARS) change after catheter ablation (CA) · 6 months after CA
- LARS improved from baseline to 6 months
- 29.7% ± 7.9% to 32.1% ± 6.7%; P < 0.001
Baseline LARS + PA-TDI duration for postprocedural left atrial (LA) function
- Combination provided enhanced predictive value
- P < 0.001
Baseline characteristics by PA-TDI duration
- No significant difference in age, sex and AF risk factors
Original publication
Total Atrial Conduction Time as a Predictor of Left Atrial Functional Recovery in Atrial Fibrillation. JACC Adv. Published 16 September 2025. doi:10.
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