Pulmonary vascular disease & thromboembolism
Pre-Existing Pulmonary Hypertension Impact on In-Hospital Outcomes of Cardiac Implantable Electrical Device Implantation
Authors' conclusion
Pre-existing PH in patients undergoing CIED implantation was associated with increased risk for respiratory complications as well as in-hospital mortality in a nationwide, all-comer registry.
Study context
- Population
- Patients hospitalized in the United States between 2016 and 2019 who underwent cardiac implantable electronic device (CIED) implantation; patients with any CIED in situ excludedestimated total undergoing CIED implantation, 74,150 (10.3%) with pre-existing pulmonary hypertension (PH)
- Participants
- 718,980 patients
- Exposure
- PH patients vs non-PH patients undergoing CIED implantation
- PH patientsn = 74,150
- Outcome
- Total complications
- Follow-up
- In-hospital
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
In-hospital mortality · higher in PH patients
P < 0.001
Multivariable analyses
- PH an independent predictor for respiratory complications, total complications, and in-hospital mortality
Baseline characteristics
- PH patients were older, had higher Charlson Comorbidity Index, and were more often implanted with implantable cardioverter defibrillators and cardiac resynchronization therapy devices
Original publication
Pre-Existing Pulmonary Hypertension Impact on In-Hospital Outcomes of Cardiac Implantable Electrical Device Implantation. JACC Adv. Published 13 May 2025. doi:10.
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