Heart failure & cardiomyopathies

Predicted Heart Mass: A Tale of 2 Ventricles

Circ Heart FailPublished Retrospective cohort study

Authors' conclusion

The association between donor-recipient PHM match and the risk of graft failure after heart transplantation can be further understood as risk attributable to LV undersizing and RV oversizing.

Study context

Population
Adult heart transplant recipients, UNOS database, 2000–2018
Participants
34,976 recipients
Exposure
Separate left ventricular (LV) and right ventricular (RV) predicted heart mass (PHM) vs total PHM for donor-recipient size matching
Outcome
Graft failure
Follow-up
1 year

Main finding

As reported in the abstract

1-year graft failure by PHM

Net reclassification index, separate LV and RV PHM vs total PHM

8.5%

95% CI 5.3%–11.7%

Nonevent net reclassification index

9.1%

Event net reclassification index

−0.6%

Observational data: associations, not effects.

Original publication

Predicted Heart Mass: A Tale of 2 Ventricles. Circ Heart Fail. Published 21 August 2023. doi:10.1161/circheartfailure.120.008311

Composed by AI from the published abstract and checked against it. How Briefs are made →

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