Heart failure & cardiomyopathies

Predicting new-onset heart failure hospitalization of patients with atrial fibrillation: development and external validations of a risk score

Eur Heart J Qual Care Clin OutcomesPublished Risk prediction model development and external validation study

Authors' conclusion

The novel risk model with four readily available clinical characteristics and biomarkers performed well in predicting new-onset HF admission in patients with AF.

Study context

Population
Patients with atrial fibrillation (AF) without a history of heart failure (HF)
Participants
2,857 vs 2,516
Comparison
RAFFINE vs SAKURA
  • RAFFINEn = 2,857
  • SAKURAn = 2,516
Outcome
New-onset HF admission
Methodological detailsmulticentre, prospective, observational registries
  • Multicentre
  • Prospective
  • Observational registries

Performance

As reported in the abstract

Risk model performance for new-onset HF admission
AUC, derivation cohort
0.80 (95% CI 0.76-0.84)
Hosmer-Lemeshow, derivation cohort
P = 0.257
AUC, validation cohort
0.78 (95% CI 0.74-0.83)
Hosmer-Lemeshow, validation cohort
P = 0.475

Further findings

Incident HF · median follow-up 1396 (IQR 1078-1820) and 1168 (IQR 844-1309) days

Original publication

Predicting new-onset heart failure hospitalization of patients with atrial fibrillation: development and external validations of a risk score. Eur Heart J Qual Care Clin Outcomes. Published 20 December 2022. doi:10.1093/ehjqcco/qcac085

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.