Valvular & structural heart disease
Predictors of pacemaker implantation in aortic regurgitation patients treated with a dedicated transcatheter heart valve
Authors' conclusion
Overall, 24.1% of patients undergoing TAVI with the JVTS required a new PPI. While rates of new PPI were strongly associated with pre-existing first-degree atrioventricular block and right bundle branch block using the JVTS, no modifiable risk factors were identified.
Study context
- Population
- Patients with aortic regurgitation without prior permanent pacemaker implantation (PPI) who underwent transfemoral transcatheter aortic valve implantation (TAVI) with the JenaValve Trilogy System (JVTS)patients without prior PPI who underwent transfemoral TAVI with the JVTS
- Participants
- 141 patients
- Exposure
- Baseline and procedural parameters between patients with and without new PPI at discharge
- Patients with new PPI at dischargen = 34
- Outcome
- Baseline characteristics
Main finding
As reported in the abstract
Median age, years
81 (interquartile range [IQR] 76-85)
Female
41%
Median European System for Cardiac Operative Risk Evaluation (EuroSCORE) II
3.6%
IQR 2.0–6.4
Observational data: associations, not effects.
Further findings
New PPI · At discharge
- Patients requiring a new PPI
- 34 patients (24.1%)
Predictors of new PPI
- Pre-existing first-degree atrioventricular block and right bundle branch block identified as independent predictors of new PPI
- Anatomical characteristics, including annular and left ventricular outflow tract perimeters, were not predictive
- Implantation depth and valve oversizing not statistically different between patients with or without new PPI
- Logistic regression models
Original publication
Predictors of pacemaker implantation in aortic regurgitation patients treated with a dedicated transcatheter heart valve. EuroIntervention. Published 16 June 2025. doi:10.
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