Predictors of target lesion revascularisation after drug-eluting stent implantation for calcified nodules: an optical coherence tomography study
Authors' conclusion
Factors such as younger age, haemodialysis, eruptive CNs, dark CNs, disrupted fibrous tissue, or irregular protrusions were independently related to TLR in patients with CNs.
Study context
- Population
- Patients with calcified nodules undergoing optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) with drug-eluting stent
- Participants
- 108 patients
- Outcome
- TLR (stent failure)
- Follow-up
- Median 523 days
Methodological detailsmulticentre, observational, consecutive patients, Dark vs bright calcified nodules (CNs) defined by half width of signal attenuation greater or lower than 332
- Multicentre
- Observational
- Consecutive patients
- Dark vs bright CNs defined by half width of signal attenuation greater or lower than 332
Main finding
As reported in the abstract
TLR
Patients with target lesion revascularisation (TLR)
25
23.1%
5-year cumulative incidence of TLR
32.6%
Observational data: associations, not effects.
Further findings
In-stent CNs at follow-up OCT
- Prevalence significantly higher in TLR than non-TLR group
Original publication
Predictors of target lesion revascularisation after drug-eluting stent implantation for calcified nodules: an optical coherence tomography study. EuroIntervention. Published 5 June 2023. doi:10.
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