PreHEART score for emergency medical services triage of chest pain: a randomised trial
Primary result · Hierarchical composite of unexpected serious adverse eventsResult — go to the resultWin ratio 1.01 95% CI 0.89–1.16Authors' conclusion
PreHEART-guided EMS conveyance was non-inferior to usual care for serious adverse events, reduced emergency department presentations and costs, and was associated with increased ACS detection and coronary angiography in women.
Study context
- Population
- Adults attended by EMS for undifferentiated chest painadults attended by EMS for undifferentiated chest pain, randomised
- Participants
- 5,170 adults
- Comparison
- A conveyance decision guided by the prehospital PreHEART score versus usual care
- Primary endpoint
- hierarchical composite of unexpected serious adverse events
- Follow-up
- 3 days
Methodological detailsconducted in the Netherlands by Emergency Medical Services
- Conducted in the Netherlands by Emergency Medical Services
Primary result
As reported in the abstract
Win ratio
1.01
95% CI 0.89–1.16
P < 0.001
PreHEART-guided carevs usual care
win ratio 1.01 (95% CI 0.89–1.16); P < 0.001
Further findings
Non-conveyance
| Outcome | RR |
|---|---|
| 30-day emergency presentations | 0.88 |
| ACS diagnosis and angiography in women (subgroup)Acute coronary syndrome (ACS) diagnosis in women, increased | 1.48 |
| ACS diagnosis and angiography in women (subgroup)Angiography in women, increased | 1.66 |
- Acute coronary syndrome (ACS) diagnosis and angiography in women (subgroup): multiplicative interactions were nominally significant but not after Holm correction
Costs
- Lowered costs
- -€345
Safety
- No deaths within 3 days among 1526 non-conveyed patients
- 1526
Original publication
PreHEART score for emergency medical services triage of chest pain: a randomised trial. Heart. Published 29 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →