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Coronary disease & ACSCohort study

Preoperative Angiographic Washout and Coronary Artery Bypass Graft Patency

JACC AdvPublished

  • single-center retrospective study
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Authors' conclusion

Automated quantification of preoperative angiographic contrast washout is feasible and associated with CABG patency, supporting CIP downslope as a potential angiography-derived marker of target-vessel outflow.

Study context

Population
Patients undergoing coronary artery bypass graft (CABG) from 2021 to 2024 with preoperative coronary angiography and postoperative graft imaging by invasive angiography or computed tomography angiographypatients, 201 bypassed target vessels analyzed
Participants
107 patients
Exposure
Each 1-SD shift toward a shallower CIP downslope and odds of graft failure
  • patentn = 152
  • graft failuren = 49
Outcome
Graft failure, defined as graft occlusion or stenosis

Main finding

As reported in the abstract

patent

152

events

graft failure

49

events

Each 1-SD shift toward a shallower CIP downslopeOdds ratio (95% CI)P value
univariable generalized estimating equations analysis; higher odds of graft failure
1.71(1.19–2.47)
P = 0.004
after adjustment for age, sex, diabetes mellitus, and current smoking; higher odds of graft failure
1.77(1.22–2.57)
P = 0.003

Each 1-SD shift toward a shallower CIP, as printed

Observational data: associations, not effects.

Further findings

Graft failure hazard by downslope threshold of −3,158

ComparisonHR (95% CI)P value
faster washout · lower failure hazard with faster washout0.51 (0.28–0.90)log-rank P = 0.0193

Model discrimination

area under the curve (modest)
0.67; 95% CI: 0.62-0.78

Original publication

Preoperative Angiographic Washout and Coronary Artery Bypass Graft Patency. JACC Adv. Published 10 September 2026. doi:10.1016/j.jacadv.2026.103204
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Summarised from the published abstract; every number is checked against it