Arrhythmias & electrophysiology
Preprocedural Screening Tool to Guide Nonpulmonary Vein Trigger Testing in First-Time Atrial Fibrillation Ablation
Authors' conclusion
A preprocedural screening tool can classify patients based on their risk of non-PV triggers during first-time AF ablation.
Study context
- Population
- Patients undergoing first-time atrial fibrillation (AF) ablation with non-PV trigger provocative maneuvers or spontaneous non-PV trigger firing, Hospital of the University of Pennsylvania, 2018–2022163 (8.0%) with non-PV triggers
- Participants
- 2,038 patients
- Exposure
- Low-risk vs Intermediate-risk vs High-risk
- Outcome
- Non-PV triggers during first-time AF ablation (non-PV ectopic beats triggering AF or sustained focal atrial tachycardia)
Methodological detailssingle-centre, risk score development, bootstrap internal validation
- Single-centre
- Risk score development
- Bootstrap internal validation
Main finding
As reported in the abstract
Risk of non-PV triggers by risk score category
Risk of non-PV triggers by risk score category
Share of procedures
- Female sex (1 point), OR
- 1.90 (95% CI 1.36-2.67)
- Sinus node dysfunction (1 point), OR
- 1.84 (95% CI 1.04-3.24)
- Prior cardiac surgery (1 point), OR
- 2.26 (95% CI 1.45-3.53)
- Moderate to severe left atrial enlargement (2 points), OR
- 3.43 (95% CI 2.46-4.79)
- Cardiac sarcoidosis/amyloidosis (4 points), OR
- 7.24 (95% CI 3.03-17.33)
- Optimism-adjusted C statistic, bootstrap internal validation
- 0.715 (95% CI 0.678-0.751)
Observational data: associations, not effects.
Original publication
Preprocedural Screening Tool to Guide Nonpulmonary Vein Trigger Testing in First-Time Atrial Fibrillation Ablation. Circ Arrhythm Electrophysiol. Published 20 December 2024. doi:10.
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