Heart failure & cardiomyopathies
Prognosis Evaluation of Chronic Inflammatory Cardiomyopathy with Ring-Like Late Gadolinium Enhancement
Authors' conclusion
For infl-CMP patients with ring-like LGE on CMR, low BMI and RVCI were associated with a poor prognosis. LV-PCSBasal with a cut-off of -7.95% can add prognostic value for patients with infl-CMP who have ring-like LGE.
Study context
- Population
- Consecutive patients with clinically suspected myocarditis; chronic inflammatory cardiomyopathy with ring-like late gadolinium enhancement (LGE)
- Participants
- 47 vs 72
- Exposure
- Ring-like LGE vs other LGE pattern on cardiac magnetic resonance (CMR)
- Ring-like LGEn = 47
- Other LGE patternn = 72reference
- Outcome
- Major (cardiac death, resuscitated cardiac arrest, ventricular assist device, transplantation, appropriate ICD shock) and minor (HF rehospitalization, sustained AF) adverse CV events
- Follow-up
- Mean 70.15 ± 45.68 months
Main finding
As reported in the abstract
Adverse cardiac events:
- Major
- Minor
| Group | Value | Deaths | HF hospitalizations | Sustained AF |
|---|---|---|---|---|
| Ring-like LGE | 31.11% | 7 (15.56%) | 6 (13.33%) | 1 (2.22%) |
Ring-like LGE
Value31.11%
Deaths7 (15.56%)
HF hospitalizations6 (13.33%)
Sustained AF1 (2.22%)
Observational data: associations, not effects.
Further findings
Independent predictors of long-term outcome in ring-like LGE (multivariable Cox)
| HR (95% CI) | P value | ||
|---|---|---|---|
| BMI | 0.54 (0.40–0.73) | P = 0.000 | |
| RVCIRight ventricle cardiac index | 0.31 (0.14–0.71) | P = 0.002 | |
| LV-PCSbasalLV basal peak circumferential strain | 1.26 (1.11–1.43) | P = 0.000 | |
| 0.10.31310Hazard ratio (log scale) |
ROC cut-off of LV-PCSBasal
- Cut-off of LV-PCSBasal; added prognostic value to body mass index (BMI) and right ventricle cardiac index (RVCI)
- −7.95%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prognosis Evaluation of Chronic Inflammatory Cardiomyopathy with Ring-Like Late Gadolinium Enhancement. ESC Heart Fail. Published 26 February 2023. doi:10.
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