Heart failure & cardiomyopathies
Prognosis of cardiac resynchronization therapy (CRT)-treated and CRT-untreated unselected population with left bundle branch block (LBBB) in Stockholm County
Authors' conclusion
In an unselected LBBB population, CRT is underused but of great value for HF patients.
Study context
- Population
- Unselected patients with LBBB and QRS > 150 ms, Stockholm County (central electrocardiogram (ECG) database and national registers)1,053 with class I CRT indication
- Participants
- 5,359 patients
- Exposure
- CRT vs no CRT
- Outcome
- Death, CV death and HF hospitalization according to CRT use
Methodological detailsregistry-based, unselected real-world population, Median age 76 years, 36% female
- Registry-based
- Unselected real-world population
- Median age 76 years, 36% female
Main finding
As reported in the abstract
Outcomes with CRT among patients with class I indication for CRT
CRT vs No CRTHazard ratio (95% CI)
Death
0.45(0.36–0.57)
CV death
0.47(0.35–0.63)
HF hospitalization
0.56(0.48–0.66)
- CRT received among patients with class I indication
- 60%
- Median delay to CRT
- 137 days
Observational data: associations, not effects.
Further findings
Heart failure (HF) history and incident HF
- Previous history of HF at index ECG
- 41%
- Developed HF
- 27%
Predictors of CRT use
- Age over 75 years, dementia and COPD predicted CRT non-use
- Having a pacing/defibrillator device independently predicted CRT use
Original publication
Prognosis of CRT-treated and CRT-untreated unselected population with LBBB in Stockholm County. Europace. Published 5 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →