Heart failure & cardiomyopathies
Prognostic Value of Left Atrial Reverse Remodelling in Patients Hospitalized with Acute Decompensated Heart Failure
Authors' conclusion
LARR in the early vulnerable phase after hospitalization for ADHF was associated with better long-term clinical outcomes.
Study context
- Population
- Patients hospitalized for acute decompensated heart failure (HF) with echocardiography at admission and discharge, 2015–2019of 861 hospitalized
- Participants
- 363 patients
- Exposure
- LA reverse remodelling (LARR) vs non-LARR
- Outcome
- CV death and rehospitalization for acute decompensated HF (ADHF)
- Follow-up
- 34.0 ± 20.2 months
Methodological detailsFollow-up echocardiogram 13.0 [9.5, 20] days after admission, LARR cut-off from median LAVI reduction rate of 7.02%
- Follow-up echocardiogram 13.0 [9.5, 20] days after admission
- LARR cut-off from median LAVI reduction rate of 7.02%
Main finding
As reported in the abstract
34.0 ± 20.2 months
Primary endpoint reached (overall)
117 patients
32.2%
Observational data: associations, not effects.
Further findings
Subgroups: persistent/permanent AF; non-HFrEF
- Similar findings in subgroup analyses
Brain natriuretic peptide (BNP) responders (>70% relative BNP reduction)
- Non-LARR among BNP responders
- 41.6%
- BNP responders without LARR had worse prognoses
Original publication
Prognostic Value of Left Atrial Reverse Remodelling in Patients Hospitalized with Acute Decompensated Heart Failure. ESC Heart Fail. Published 26 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →