Prognostic Value of Murray Law-Based Quantitative Flow Ratio (QFR) (μQFR)-Guided Virtual Percutaneous Coronary Intervention (PCI) in Patients With Physiological Ischemia
Primary result · Optimal physiological outcome (post-PCI μQFR ≥0.90)Result — go to the resultAbsolute difference 9.1% 95% CI 4.53–13.76Authors' conclusion
The QUITE RIGHT study showed that the μQFR-guided virtual PCI strategy is superior to angiography-guided PCI in terms of physiological outcomes.
Study context
- Population
- Patients with physiological ischemia undergoing PCI
- Participants
- 622 patients666 vessels
- Comparison
- μQFR-guided virtual PCI vs angiography-guided PCI
- Primary endpoint
- Proportion of target vessels with post-PCI μQFR ≥0.90 (optimal post-PCI physiological outcome)
- Follow-up
- Post-PCI
Methodological detailsprospective, multicentre, blinded, superiority, 1:1 randomisation
- Prospective
- Multicentre
- Blinded
- Superiority
- 1:1 randomisation
Primary result
As reported in the abstract
Optimal physiological outcome (post-PCI μQFR ≥0.90)
Absolute difference
9.1%
95% CI 4.53–13.76
P < 0.001
μQFR-guided virtual PCIvs Angiography-guided PCI
absolute difference 9.1% (95% CI 4.53–13.76); P < 0.001
Further findings
- μQFR-guided virtual PCI: better QFR value, lower contrast and x-ray dose, more appropriate stent length vs angiography-guided
Original publication
Prognostic Value of Murray Law-Based QFR (μQFR)-Guided Virtual PCI in Patients With Physiological Ischemia. Circ Cardiovasc Interv. Published 25 September 2024. doi:10.
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