Heart failure & cardiomyopathies
Prognostic Value of New Proposed Criteria for Atrial Cardiomyopathy in Patients With Heart Failure
Main finding · Composite of all-cause death and hospitalization for worsening HFResult — go to the resultHazard ratio 1.31 95% CI 1.00–1.70Authors' conclusion
AtCM defined by the proposed criteria identified patients with HF at increased risk of adverse events. Combined electrical and mechanical atrial dysfunction characterized a subgroup with markedly elevated risk, underscoring the clinical relevance of integrating both domains when diagnosing AtCM. (Development of a flail evaluation application based on deep learning; UMIN000043390).
Study context
- Population
- Symptomatic patients with chronic heart failure (HF)enrolled between January 2020 and June 2025
- Participants
- 2,046 patients
- Exposure
- Patients with atrial cardiomyopathy (AtCM) than in those without AtCM
- Outcome
- Composite of:
- All-cause death
- Hospitalization for worsening HF
- Follow-up
- Median 727 days (IQR: 518-1,119)
Methodological detailsprospectively enrolled
- Prospectively enrolled
Main finding
As reported in the abstract
Hazard ratio
1.31
95% CI 1.00–1.70
AtCMvs without AtCM
HR 1.31 (95% CI 1.00–1.70)
- Primary outcome occurred in
- 427 patients
- Incidence higher in patients with AtCM than in those without AtCM
- P < 0.001
Observational data: associations, not effects.
Further findings
- Coexistence of electrical and mechanical atrial dysfunction showed the highest risk of adverse events
Original publication
Prognostic Value of New Proposed Criteria for Atrial Cardiomyopathy in Patients With Heart Failure. JACC Adv. Published 14 August 2026. doi:10.
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