Prevention & lipids

Prognostic Value of Self-Reported Subjective Exercise Capacity in Patients With Acute Dyspnea

JACC AdvPublished Prognostic analysis of a prospective multicentre diagnostic study

Authors' conclusion

Quantification of self-reported subjective exercise capacity using the DASI provides high prognostic accuracy and may aid physicians in risk stratification.

Study context

Population
Unselected patients presenting with acute dyspnea to the EDeligible for analysis
Participants
1,019 patients
Comparison
Duke Activity Status Index (DASI) vs BNP for prognostic accuracy
Outcome
Prognostic accuracy (C-index) of DASI and BNP for all-cause mortality
Follow-up
90 and 720 days

Performance

As reported in the abstract

720-day all-cause mortality by DASI quartile · 720 days
Hazard ratio (95% CI)
DASI Q1vs DASI Q4aHR 6.1 (95% CI 3.7-10.1)
9.1(5.5–14.9)
DASI Q2vs DASI Q4aHR 4.4 (95% CI 2.6-7.3)
6.4(3.9–10.6)
DASI Q3vs DASI Q4aHR 2.4 (95% CI 1.4-4.0)
3.2(1.9–5.5)
720-day mortality C-index, DASI vs BNP
0.67 vs 0.62; P = 0.024
Deaths within 90 days
75 (7%)
Deaths within 720 days
297 (29%)

Original publication

Prognostic Value of Self-Reported Subjective Exercise Capacity in Patients With Acute Dyspnea. JACC Adv. Published 26 May 2023. doi:10.1016/j.jacadv.2023.100342

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