Arrhythmias & electrophysiology

Progressive outcomes of bundle branch reentrant ventricular tachycardia in patients without structural heart disease

Heart RhythmPublished Retrospective cohort study

Authors' conclusion

Further deterioration of His-Purkinje system conduction was observed in young BBRT patients without SHD after ablation.

Study context

Population
Patients with bundle branch reentrant VT (BBRT) without structural heart disease after ablationmedian age 20 (11–48) years
Participants
11 patients
Exposure
Follow-up vs Postablation
Outcome
Long-term prognosis: progression of ECG and echocardiographic parameters
Follow-up
Median 72 months
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

ECG conduction parameters · median 72 months
GroupPR intervalQRS duration
Follow-up206 (158-360) ms187 (155-240) ms
Postablation188 (158-300) ms164 (130-178) ms

PR interval

Follow-up206 (158-360) ms
Postablation188 (158-300) ms

QRS duration

Follow-up187 (155-240) ms
Postablation164 (130-178) ms
  • Follow-up vs Postablation: P = 0.018 — PR interval
  • Follow-up vs Postablation: P = 0.008 — QRS duration
Clinical deterioration or events
8
Sudden death
1
Complete heart block and reduced left ventricular ejection fraction (LVEF)
3
Significantly reduced LVEF
2
Prolonged PR interval
2

Observational data: associations, not effects.

Further findings

≥1 potential pathogenic candidate variant on gene panel

Patients with ≥1 potential pathogenic candidate variant (of 10 tested, excluding sudden death)
6

Original publication

Progressive outcomes of bundle branch reentrant ventricular tachycardia in patients without structural heart disease. Heart Rhythm. Published 2 March 2023. doi:10.1016/j.hrthm.2023.02.027

Composed by AI from the published abstract and checked against it. How Briefs are made →

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