Arrhythmias & electrophysiology
Progressive outcomes of bundle branch reentrant ventricular tachycardia in patients without structural heart disease
Authors' conclusion
Further deterioration of His-Purkinje system conduction was observed in young BBRT patients without SHD after ablation.
Study context
- Population
- Patients with bundle branch reentrant VT (BBRT) without structural heart disease after ablationmedian age 20 (11–48) years
- Participants
- 11 patients
- Exposure
- Follow-up vs Postablation
- Outcome
- Long-term prognosis: progression of ECG and echocardiographic parameters
- Follow-up
- Median 72 months
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
ECG conduction parameters · median 72 months
| Group | PR interval | QRS duration |
|---|---|---|
| Follow-up | 206 (158-360) ms | 187 (155-240) ms |
| Postablation | 188 (158-300) ms | 164 (130-178) ms |
PR interval
Follow-up206 (158-360) ms
Postablation188 (158-300) ms
QRS duration
Follow-up187 (155-240) ms
Postablation164 (130-178) ms
- Follow-up vs Postablation: P = 0.018 — PR interval
- Follow-up vs Postablation: P = 0.008 — QRS duration
- Clinical deterioration or events
- 8
- Sudden death
- 1
- Complete heart block and reduced left ventricular ejection fraction (LVEF)
- 3
- Significantly reduced LVEF
- 2
- Prolonged PR interval
- 2
Observational data: associations, not effects.
Further findings
≥1 potential pathogenic candidate variant on gene panel
- Patients with ≥1 potential pathogenic candidate variant (of 10 tested, excluding sudden death)
- 6
Original publication
Progressive outcomes of bundle branch reentrant ventricular tachycardia in patients without structural heart disease. Heart Rhythm. Published 2 March 2023. doi:10. 1016/ j. hrthm. 2023. 02. 027
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