Arrhythmias & electrophysiology
Psychiatric disorders and the risk of atrial fibrillation: a Swedish population-based cohort study
Authors' conclusion
Several PDs were linked to increased risks of developing AF.
Study context
- Population
- Parents of live-born children in the Swedish Medical Birth Register 1973–2014, followed 2001–2023
- Participants
- 3,815,546 parents82.6 million person-years
- Exposure
- Psychiatric disorders vs no psychiatric disorder
- Outcome
- Incident AF
- Follow-up
- January 1, 2001 to December 31, 2023
Methodological detailssibling comparison, Swedish national registers
- Sibling comparison
- Swedish national registers
Main finding
As reported in the abstract
Incident AF by overall PD
PD vs No PDAdjusted hazard ratio (95% CI)
Whole cohort
1.28(1.27–1.29)
Sibling analysis
1.32(1.29–1.35)
- Atrial fibrillation (AF) diagnosed during follow-up
- 213,048 (5.58%)
Observational data: associations, not effects.
Further findings
AF risk over follow-up time
- Associations strongest early in follow-up, progressively weakened over time, but persisted through the whole follow-up
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Psychiatric disorders and the risk of atrial fibrillation: a Swedish population-based cohort study. Eur J Prev Cardiol. Published 15 December 2025. doi:10.
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