Hypertension

Public reporting of black participation in anti-hypertensive drug clinical trials

Am Heart JPublished Cross-sectional study

Authors' conclusion

Despite Black Americans carrying the highest burden of disease for essential hypertension, they are underrepresented in anti-hypertension clinical trials and their overall participation has decreased between 2010 and 2020. In addition, there is major underreporting of trial participant race.

Study context

Population
Antihypertensive drug trials on ClinicalTrials.gov reporting results 2010–2020trials
Participants
97 trials
Exposure
Industry vs non-industry sponsored trials
Outcome
Representation of Black participants by trial sponsorship type
Methodological detailsClinicalTrials.gov registry analysis
  • ClinicalTrials.gov registry analysis

Main finding

As reported in the abstract

Percent of Black patients enrolled
  • Minimal differences in percent of Black patients enrolled by sponsorship type

Observational data: associations, not effects.

Further findings

Non-reporting of participant race

Time from study completion to results reporting on ClinicalTrials.gov

Original publication

Public reporting of black participation in anti-hypertensive drug clinical trials. Am Heart J. Published 11 January 2023. doi:10.1016/j.ahj.2023.01.001

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.