Valvular & structural heart disease
Pulmonary Congestion Assessed by Lung Ultrasound in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation: Prevalence and Prognostic Implications
Main finding · Composite endpointResult — go to the resultHazard ratio 2.764 95% CI 1.114–6.857Authors' conclusion
Lung ultrasonography reveals a high prevalence of PC in patients with severe AS undergoing TAVI, which is significantly reduced by the procedure. Pre-TAVI PC, measured by LUS, is an independent predictor of 1-year clinical outcome.
Study context
- Population
- Patients with severe aortic stenosis (AS) referred for transcatheter aortic valve implantation (TAVI)
- Participants
- 127 patients
- Exposure
- Pre-TAVI lung ultrasound (LUS) pulmonary congestion vs no congestion
- Pre-TAVI LUS-PCn = 65
- Outcome
- Composite of:
- All-cause mortality
- HF hospitalisation
- Urgent medical visits for worsening dyspnoea
- Follow-up
- 12-month follow-up
Methodological detailssingle-centre
- Single-centre
Main finding
Composite endpoint · median follow-up 12 (12-17) months
Hazard ratio
2.764
95% CI 1.114–6.857
P = 0.028
LUS-PCvs No LUS-PC
HR 2.764 (95% CI 1.114–6.857); P = 0.028
As reported in the abstract
- Patients meeting the composite endpoint
- 25 (19.6%)
Observational data: associations, not effects.
Further findings
Prevalence of LUS-PC, pre- vs after TAVI · within 72 h after TAVI
- LUS-PC after TAVI: 28 patients (22% vs. 51% pre-TAVI)
- P < 0.001
- Median B-lines score after vs pre-TAVI: 4 (IQR 0-11) vs 11 (IQR 6-19)
- P < 0.001
Original publication
Pulmonary Congestion Assessed by Lung Ultrasound in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation: Prevalence and Prognostic Implications. Eur J Heart Fail. Published 16 July 2024. doi:10.
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