Valvular & structural heart disease

Near-infrared spectroscopy-intravascular ultrasound to improve assessment of coronary artery disease severity in patients referred for transcatheter aortic valve implantation (The IMPACTavi registry): Design and rationale

Am Heart JPublished Prospective cohort registry

Study context

Population
Patients referred for transcatheter aortic valve implantation (TAVI) with angiographic evidence of coronary artery disease (CAD)
Planned comparison
Near-infrared spectroscopy and intravascular ultrasound (NIRS-IVUS) positive vs NIRS-IVUS negative
Primary endpoint
Major adverse CV events
Follow-up
24-month follow-up
Methodological detailsdesign and rationale, non-randomized, observational, multicenter, Patients receive NIRS-IVUS imaging at pre-TAVI coronary angiography and are followed up to 24 months
  • Design and rationale
  • Non-randomized
  • Observational
  • Multicenter
  • Patients receive NIRS-IVUS imaging at pre-TAVI coronary angiography and are followed up to 24 months

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Near-infrared spectroscopy-intravascular ultrasound to improve assessment of coronary artery disease severity in patients referred for transcatheter aortic valve implantation (The IMPACTavi registry): Design and rationale. Am Heart J. Published 12 June 2023. doi:10.1016/j.ahj.2023.06.004

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