Arrhythmias & electrophysiology
QRS complex and T wave planarity for the efficacy prediction of automatic implantable defibrillators
Authors' conclusion
The analysed data suggest that QRS and T wave non-planarity might offer distinction between patients who are at greater risk of death despite ICD protection and those who are likely to use the defibrillator protection.
Study context
- Population
- Recipients of primary prophylactic implantable cardioverter-defibrillators (ICDs) (21.4% females, median age 65 years, 61.5% ischaemic heart disease (IHD))
- Participants
- 1,948 recipients
- Exposure
- QRS and T wave non-planarity of pre-implant ECG vector loops as predictors of outcome
- Outcome
- (a) All-cause mortality despite ICD protection and (b) appropriate ICD shocks
- Follow-up
- 5-year after device implantation
Main finding
As reported in the abstract
- Deaths during follow-up
- 294
- Appropriate ICD shocks
- 162
- QRS non-planarity and all-cause mortality: HR 1.339 (95% CI 1.165 to 1.540)
- p<0.001
- T wave non-planarity and appropriate ICD shocks (multivariable Cox): HR 1.364 (1.180 to 1.576); only ECG-derived index significantly associated
- p<0.001
Observational data: associations, not effects.
Original publication
QRS complex and T wave planarity for the efficacy prediction of automatic implantable defibrillators. Heart. Published 15 September 2023. doi:10.
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